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Pantabangan is best known for Pantabangan Dam and its huge reservoir, which has become a popular destination for island hopping, kayaking, fishing, and scenic trips. The old town of Pantabangan was submerged during construction of the dam in the 1970s, and parts of its church and other ruins can reappear when water levels fall. Mountains, forests, and the wide lake give Pantabangan some of the most dramatic scenery in Nueva Ecija.

San Antonio is known for its agricultural lands and its location close to several major nature destinations in eastern Nueva Ecija. The town has farms, rivers, and rural areas that provide a quieter alternative to the larger urban centers nearby. Its mostly flat terrain gradually rises toward the foothills of the Sierra Madre.

Cuyapo is an agricultural town known for its peaceful farming communities and traditional local crop harvests. Its flat to rolling terrain is surrounded by productive rice fields and active community markets.

Gabaldon is a scenic valley town famous for its popular eco-tourism sites, refreshing natural springs, and the historic Gabaldon-style school buildings. Its rugged topography features sweeping green mountain ranges and winding rivers.

The Science City of Muñoz is nationally known as a center of agricultural science and technology, with major research institutions and Central Luzon State University shaping its identity. The city has at least 16 science and research institutions, making agricultural and science tourism an important part of its development. Its attractions include research centers, museums, farms, and cultural properties connected with Philippine agriculture.